Paracetamol affects everyone differently, based on: size, weight and health whether the person is used to taking it whether other drugs are taken around the same time the amount taken. Side effects The most common side effects of paracetamol are: drowsiness and fatigue rashes and itching. Abdominal pain, nausea, vomiting Liver problems Seizures Coma and death. Tiredness Breathlessness Bluish tinge to fingers and lips Anaemia low red blood cell count Liver and kidney damage 1.
Upfal J. Melbourne: Black Inc. Tittarelli, R. Hepatotoxicity of paracetamol and related fatalities. The labels on liquid paracetamol contain clear instructions. It's dangerous to take more than the recommended dose as you may damage your liver, which may be irreversible and fatal. Paracetamol is sold under a variety of brand names, which can be confusing and lead to someone taking more paracetamol than the safe recommended level. Check the pack before taking any medication.
Paracetamol may be recommended for children if there is pain or fever after a vaccination. If your child has a high temperature and this is making them uncomfortable, paracetamol can be given to help ease any discomfort.
Seek medical advice if the fever does not get better. A doctor may advise regular paracetamol for infants younger than one month old, but don't give regular paracetamol to an infant as young as this unless advised to do so by a doctor.
Paracetamol has been in general use for more than 50 years, but the way it works to reduce pain and fever is not fully understood. Paracetamol begins to ease pain and lower a high temperature about 30 minutes after a dose is taken. Its effects usually last for about 4 to 6 hours. This may damage your liver and can be fatal. Paracetamol is the recommended painkiller for people taking warfarin.
Long-term use of paracetamol may increase the effect of warfarin, which can increase the risk of bleeding. However, this is unlikely to happen with the occasional use of paracetamol. Paracetamol is considered the first choice of painkiller if you are pregnant since it has been taken by large numbers of pregnant women without any adverse effect on the mother or baby. As with any medicine taken during pregnancy, pregnant women should seek medical advice before taking paracetamol.
If you take paracetamol when pregnant, make sure you take it at the lowest effective dose and for the shortest possible time. If you take paracetamol when breastfeeding, make sure you take it at the recommended dose and for the shortest possible time. People react differently to medicines. Just because a side effect is listed doesn't mean you will experience the side effect.
Take the dose as soon as you remember, and then the next dose at least 4 hours later. Doses of paracetamol should be at least four hours apart. Don't take more than the recommended dose over a 24 hour period. Check the information leaflet that comes with your medicine. It should give you advice about what to do. Call triple zero immediately and ask for an ambulance if you or someone you know has taken more than the recommended dose of paracetamol and have symptoms of overdose.
Over the same period, concerns over the long-term adverse effects of paracetamol use have increased, initially in the field of hypertension, but more recently in other areas as well. The evidence base for the adverse effects of chronic paracetamol use consists of many cohort and observational studies, with few randomized controlled trials, many of which contradict each other, so these studies must be interpreted with caution.
Nevertheless, there are some areas where the evidence for harm is more robust, and if a clinician is starting paracetamol with the expectation of chronic use it might be advisable to discuss these side effects with patients beforehand.
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